NAD+
Nicotinamide adenine dinucleotide (NAD+) is a molecule found in every cell of the human body, essential for maintaining cellular health and overall vitality. Often referred to as a “coenzyme of life,” NAD+ plays a central role in energy production, DNA repair, and cellular communication. These cellular processes and functions are critical for maintaining tissue and metabolic balance and for healthy aging.
NAD+ is a coenzyme, meaning it helps enzymes perform their functions more efficiently. This molecule is essential for converting the food you eat into the energy your body needs. It also plays a role in repairing damaged DNA, reducing inflammation, and regulating your sleep-wake cycle.
As we age, NAD+ levels naturally decline. This decrease can contribute to fatigue, slower metabolism, reduced cognitive function, and other age-related changes. Lifestyle factors such as poor diet, stress, and lack of sleep can further deplete NAD+ levels, making it harder for your body to function at its best. Many of these age associated diseases can be slowed down and even reversed by restoring NAD+ levels.
NAD+ has several key roles in the body, including:
- Energy Production: NAD+ helps your mitochondria – known as the “power plants” of your cells – produce energy. This energy fuels every activity, from thinking and breathing to exercising and digesting food.
- DNA Repair: Damage to DNA occurs daily due to environmental factors and normal cellular activity. NAD+ supports repair mechanisms, helping to maintain the integrity of your genetic material.
- Anti-Aging Support: By promoting cellular health, NAD+ may slow some processes of aging, improving skin elasticity, energy levels, and mental clarity.
- Brain Health: NAD+ supports neuron function and may protect against cognitive decline, enhancing focus, memory, and overall brain performance.
Immune Function
NAD+ plays a role in modulating the immune response. It influences inflammation and supports the body’s ability to respond to infections and other immune challenges.
- Metabolic Regulation: Maintaining adequate NAD+ levels can support healthy metabolism, weight management, and insulin sensitivity.
NAD+ supplementation or therapy may be beneficial for a wide range of people, including:
- Individuals with Chronic Fatigue: If you feel drained despite adequate rest, boosting NAD+ may help restore energy levels.
- Those Facing Age-Related Decline: NAD+ supplementation can support cellular repair and overall vitality as you age.
- People with High-Stress Lifestyles: Stress depletes NAD+ levels. Replenishing this coenzyme may help mitigate the effects of stress on your body.
- Athletes: Enhanced energy production and faster recovery may benefit those with physically demanding lifestyles.
- Anyone Interested in Preventative Health: Maintaining optimal NAD+ levels can support long-term wellness and resilience.
Maintaining or boosting NAD+ levels can be achieved through lifestyle changes, supplementation, or medical therapies:
- Dietary sources
foods rich in vitamin B3, such as fish, poultry, and whole grains, can support NAD+ production. Additionally, foods like broccoli, avocado, and peanuts contain precursors that enhance NAD+ synthesis.
- Supplementation
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are popular NAD+ precursors available as dietary supplements. These compounds are converted into NAD+ within the body and have been shown to increase NAD+ levels.
- Exercise
Regular physical activity stimulates NAD+ production by activating enzymes involved in energy metabolism and cellular repair.
NAD+ Infusions
NAD+ intravenous (IV) therapy is an emerging treatment for rapidly boosting NAD+ levels. This therapy is used at Vitality Health wellness clinic to address fatigue, cognitive decline, and other health concerns.
NAD+ is a cornerstone of cellular health, playing an integral role in energy production, DNA repair, and combating the effects of aging. While NAD+ levels naturally decline over time, targeted interventions can help support its levels, potentially improving energy, slowing aging, and enhancing overall wellness. Whether through lifestyle changes, supplements, or medical therapies, maintaining optimal NAD+ levels can significantly impact health and vitality. For those considering NAD+ supplementation or therapy, consulting with a Vitality Health provider is essential to ensure safety and efficacy. Contact us to jumpstart your journey to health and vitality.
References
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Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141. doi: 10.1038/s41580-020-00313-x. Epub 2020 Dec 22. PMID: 33353981; PMCID: PMC7963035.